SCHEMBL2247189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13816496	0.86	APP (0.63)	MEN1KMT2AKDM4EILKRORC
	SCHEMBL4807748	0.86	MAPT (0.59)	KDM4EILKRORCAPPGAA
	SCHEMBL1747940	0.82	MEN1 (0.59)	MEN1KMT2AKDM4ERECQLILK
	SCHEMBL12355589	0.78	MAPT (0.72)	MEN1KMT2AKDM4ERORCAPP
	SCHEMBL25028293	0.77	APP (0.61)	MEN1KMT2AKDM4EAPPPOLB
	SCHEMBL23170966	0.75	MAPT (0.64)	MEN1KMT2AKDM4ERORCAPP
	SCHEMBL3196637	0.75	APP (0.62)	MEN1KMT2AKDM4EILKRORC
	SCHEMBL3193978	0.75	MAPT (0.81)	MEN1KMT2AKDM4ERECQLAPP
	SCHEMBL19029213	0.75	HDAC6 (0.58)	MEN1KMT2AKDM4ERECQLRORC
	SCHEMBL27917560	0.74	APP (0.74)	KDM4EAPPGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.