Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472368 | 0.82 | NPC1 (0.47) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL23504051 | 0.80 | NPC1 (0.44) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL22472576 | 0.77 | GABRP (0.36) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL17491659 | 0.75 | NPC1 (0.66) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL20678333 | 0.71 | NPC1 (0.49) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL17507238 | 0.70 | NPC1 (0.45) | NPC1RAB9AKMT2AKDM4EPDE2A | |
| SCHEMBL18805403 | 0.70 | KMT2A (0.46) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL824419 | 0.70 | NPC1 (0.63) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL22100054 | 0.69 | NPC1 (0.47) | NPC1RAB9AKMT2AKDM4EPDE2A | |
| SCHEMBL17507245 | 0.67 | NPC1 (0.51) | NPC1RAB9AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11038137-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-06-15 | — | — | US | disclosed |
| US-10790455-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10790455-B2 | Organic electroluminescent materials and devices | ORC3, ALKBH2, ENPP3 | NPC1 4454/4885RAB9A 2730/4885GABRP 2685/4885 |
| US-11038137-B2 | Organic electroluminescent materials and devices | ORC3, NUDC, AOC1 | NPC1 4373/4885RAB9A 1454/4885GABRP 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.