Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22474221 | 1.00 | TSHR (0.39) | TSHRALDH1A1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL22474226 | 0.85 | LMNA (0.39) | TSHRALDH1A1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL22474203 | 0.83 | CYP3A4 (0.47) | TSHRALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL17900768 | 0.82 | ALDH1A1 (0.41) | TSHRALDH1A1RAB9ACYP2D6KMT2A | |
| SCHEMBL17900767 | 0.82 | ALDH1A1 (0.41) | TSHRALDH1A1RAB9ACYP2D6KMT2A | |
| SCHEMBL22474334 | 0.80 | GPR88 (0.40) | GPR88 | |
| SCHEMBL22474290 | 0.80 | MTNR1A (0.42) | TSHRALDH1A1FFAR1KMT2AMEN1 | |
| SCHEMBL1081846 | 0.79 | TSHR (0.43) | TSHRALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL20145303 | 0.79 | TSHR (0.43) | TSHRALDH1A1KMT2AMEN1HCAR2 | |
| SCHEMBL27594658 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1CYP2D6KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |