Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22474799 | 0.80 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL15868268 | 0.77 | SIGMAR1 (0.40) | HPGDALDH1A1SIGMAR1RAB9APOLB | |
| SCHEMBL20807130 | 0.76 | PARP1 (0.40) | HPGDALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL23837552 | 0.76 | MTNR1A (0.36) | RAB9AKMT2AMEN1 | |
| SCHEMBL18966760 | 0.74 | PARP1 (0.34) | — | |
| SCHEMBL23130227 | 0.74 | KMT2A (0.44) | POLBKMT2A | |
| SCHEMBL23837606 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23644550 | 0.69 | PARP1 (0.42) | ALDH1A1 | |
| SCHEMBL18089666 | 0.69 | SMN1; SMN2 (0.40) | HPGDALDH1A1SIGMAR1RAB9APOLB | |
| SCHEMBL23129889 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145936-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |