Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23837606 | 0.84 | ALDH1A1 (0.43) | KMT2A | |
| SCHEMBL17337059 | 0.80 | KMT2A (0.41) | KMT2ALMNAPOLBTHRBNAMPT | |
| SCHEMBL17337055 | 0.80 | KMT2A (0.41) | KMT2ALMNAPOLBTHRBNAMPT | |
| SCHEMBL23837552 | 0.75 | MTNR1A (0.36) | KMT2ANAMPT | |
| SCHEMBL22474799 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL22474786 | 0.74 | HPGD (0.40) | KMT2APOLB | |
| SCHEMBL20807130 | 0.72 | PARP1 (0.40) | LMNA | |
| SCHEMBL23837455 | 0.72 | TRPA1 (0.42) | KMT2ALMNAPOLBTHRBTSHR | |
| SCHEMBL18966760 | 0.70 | PARP1 (0.34) | — | |
| SCHEMBL23130114 | 0.69 | TSHR (0.37) | KMT2ALMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |