SCHEMBL2248190

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2245074	0.94	ADAMTS5 (0.60)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2246984	0.92	L3MBTL1 (0.60)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2247076	0.89	ADAMTS5 (0.68)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2246542	0.89	TDP1 (0.56)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2246551	0.89	CTSL (0.60)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2252325	0.88	ADAMTS5 (0.53)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2247683	0.87	ADAMTS5 (0.58)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2248766	0.87	ADAMTS5 (0.53)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2247378	0.86	ADAMTS5 (0.59)	ADAMTS5ADAMTS4MMP12MMP2MMP8
	SCHEMBL2244954	0.86	ADAMTS5 (0.52)	ADAMTS5ADAMTS4MMP12MMP2MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.