Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241852 | 0.87 | KIF11 (0.49) | GABRA1GABRB2PIM1PIM3LMNA | |
| SCHEMBL29376743 | 0.87 | KIF11 (0.49) | GABRA1GABRB2PIM1PIM3LMNA | |
| Ammonia Solution, Strong SCHEMBL28918843 | 0.86 | KIF11 (0.47) | GABRA1GABRB2PIM1PIM3LMNA | |
| SCHEMBL28876207 | 0.86 | KIF11 (0.47) | GABRA1GABRB2PIM1PIM3LMNA | |
| SCHEMBL7033769 | 0.81 | GAA (0.42) | GABRA1GABRB2PIM1PIM3LMNA | |
| SCHEMBL31619949 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2PIM1LMNAMAPT | |
| SCHEMBL5831594 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2PIM1LMNAMAPT | |
| SCHEMBL22482060 | 0.79 | PIM1 (0.47) | PIM1PIM3LMNAHTTALDH1A1 | |
| SCHEMBL28398379 | 0.78 | TDO2 (0.43) | GABRA1GABRB2LMNAMAPTMAPK1 | |
| SCHEMBL7291871 | 0.73 | CCR8 (0.48) | GABRA1GABRB2PIM1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308196-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308196-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, SOD1, EML4 | GABRA1 4715/4885GABRB2 4539/4885PIM1 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.