SCHEMBL2249063

SCHEMBL2249063

CCCCCCC(C(=O)OCC)C(C)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.46
GPR84 Q9NQS5 7/20 0.46
FFAR1 O14842 2/20 0.46
ZDHHC7 Q9NXF8 1/20 0.44
MAPT P10636 1/20 0.43
ABCB1 P08183 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
ACE2 Q9BYF1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436424 1.00 FAAH (0.46) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL29282542 0.92 CA2 (0.41) FAAHGPR84MAPT
SCHEMBL7070785 0.88 ZDHHC7 (0.50) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL19690704 0.88 ZDHHC7 (0.50) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL17713606 0.87 ZDHHC7 (0.46) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL13269368 0.86 ZDHHC7 (0.47) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL14763769 0.86 GPR84 (0.43) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL29186605 0.85 GPR84 (0.46) GPR84FFAR1ZDHHC7MAPTABCB1
SCHEMBL28552378 0.85 ZDHHC7 (0.58) FAAHGPR84FFAR1ZDHHC7MAPT
SCHEMBL3682993 0.85 CA1 (0.44) FAAHGPR84FFAR1ZDHHC7MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101445545-B Method for separating triptolide from thunder god vine leaves UNIV ZHEJIANG 2011-05-04 CN claimed
CN-101445545-A Method for separating triptolide from thunder god vine leaves UNIV ZHEJIANG (CN) 2009-06-03 CN claimed
CN-106278829-A Honokiol derivative, preparation and separation method and application thereof 四川大学华西医院 2017-01-04 CN disclosed
CN-106187710-A Honokiol dimer and preparative separation method thereof and purposes 四川大学 2016-12-07 CN disclosed
US-8716182-B2 Liquid aqueous crop protection formulations BASF SE (DE) 2014-05-06 US disclosed
US-20110195839-A1 Liquid Aqueous Crop Protection Formulations BASF SE (DE) 2011-08-11 US disclosed
CN-101445545-B Method for separating triptolide from thunder god vine leaves UNIV ZHEJIANG 2011-05-04 CN disclosed
CN-101445545-A Method for separating triptolide from thunder god vine leaves UNIV ZHEJIANG (CN) 2009-06-03 CN disclosed
CN-101272799-A Plant-based medicament for the treatment of liver disease PHYNOVA LTD (GB) 2008-09-24 CN disclosed
CN-101029022-A Process for producing nitrogen-containing aromatic ring derivative EISAI R&D MAN CO LTD (JP) 2007-09-05 CN disclosed
CN-101024627-A Nitrogen-containing aromatic ring derivatives EISAI R&D MAN CO LTD (JP) 2007-08-29 CN disclosed
CN-1308310-C Nitrogen-containing aromatic ring derivatives EISAI CO LTD (JP) 2007-04-04 CN disclosed
CN-1925864-A Plant-based medicament for the treatment of hepatitis c PHYNOVA LTD (GB) 2007-03-07 CN disclosed
CN-1478078-A Nitrogen-containing aromatic ring derivatives ������������ʽ���� 2004-02-25 CN disclosed
US-6225521-B1 Adhesive-matrix patch L'OREAL (FR) 2001-05-01 US disclosed
US-6191339-B1 Thermal effect patch and the use thereof L'OREAL (FR) 2001-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195839-A1 Liquid Aqueous Crop Protection Formulations AQP1, GANC, BROX FAAH 1137/4885GPR84 4544/4885FFAR1 1895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.