SCHEMBL22490881

SCHEMBL22490881

COc1c(Cl)c(OCc2ccccc2)c(Cl)c(C)c1C(=O)COC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.36
PDE4D Q08499 1/20 0.35
KCNA3 P22001 1/20 0.35
HSPA5 P11021 2/20 0.32
PTPN1 P18031 1/20 0.32
SLC5A2 P31639 2/20 0.32
SLC5A1 P13866 1/20 0.32
HPGD P15428 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22490880 0.80 TNF (0.37) PDE4DKCNA3HPGDLMNA
SCHEMBL23488282 0.79 LGALS8 (0.40) SLC6A2PDE4DKCNA3SLC5A2SLC5A1
SCHEMBL23488579 0.79 LGALS8 (0.40) SLC6A2PDE4DKCNA3SLC5A2SLC5A1
SCHEMBL23488516 0.79 LGALS8 (0.40) SLC6A2PDE4DKCNA3SLC5A2SLC5A1
SCHEMBL23488157 0.76 LGALS8 (0.44) SLC6A2PDE4DKCNA3SLC5A2SLC5A1
SCHEMBL22490898 0.75 PDE4D (0.45) PDE4DKCNA3PTPN1HPGDNPC1
SCHEMBL22490875 0.74 PARP10 (0.49) SLC6A2NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL22490933 0.74 PARP10 (0.49) SLC6A2NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL22490915 0.74 PARP10 (0.49) SLC6A2NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL23488171 0.74 LGALS8 (0.47) SLC6A2SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-3717463-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 SLC6A2 1655/4885PDE4D 1147/4885KCNA3 4345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.