Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517357 | 1.00 | LMNA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL27790942 | 0.85 | NFE2L2 (0.36) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL96067 | 0.82 | CES2 (0.43) | SLC6A2NFE2L2PDE2AL3MBTL1ALDH1A1 | |
| SCHEMBL27766137 | 0.80 | TRPA1 (0.41) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL27741876 | 0.79 | LMNA (0.40) | LMNA | |
| SCHEMBL27817041 | 0.79 | PDE2A (0.33) | PDE2A | |
| SCHEMBL27747529 | 0.79 | APLNR (0.48) | LMNAPDE2AL3MBTL1ALDH1A1 | |
| SCHEMBL84448 | 0.77 | TRPA1 (0.56) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21042111 | 0.77 | TDP1 (0.45) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL27696940 | 0.77 | LMNA (0.62) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717461-A1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | OAT Agrio Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |