Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 7/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 7/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492821 | 0.88 | CSNK2A1 (0.49) | CSNK2A1ABCG2MEN1KMT2A | |
| SCHEMBL22492843 | 0.81 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2CSNK2BCCNA2CDK2 | |
| SCHEMBL22492805 | 0.81 | CDK2 (0.57) | CSNK2A1CSNK2A2CSNK2BABCG2KCNK3 | |
| SCHEMBL22492833 | 0.81 | SIRT2 (0.48) | CCNA2CDK2MEN1NPC1RAB9A | |
| SCHEMBL22492801 | 0.78 | MAPT (0.59) | CSNK2A1KCNK3MEN1NPC1RAB9A | |
| SCHEMBL22492828 | 0.77 | CCNA2 (0.52) | CSNK2A1ABCG2CCNA2CDK2MEN1 | |
| SCHEMBL22492764 | 0.73 | RAB9A (0.52) | KCNK9MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1637630 | 0.70 | ATM (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8189003 | 0.70 | ALDH1A1 (0.60) | CSNK2A1CSNK2A2CSNK2BABCG2IDO1 | |
| SCHEMBL5612900 | 0.70 | KCNK3 (0.69) | KCNK3KCNK9MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | UNIV CALIFORNIA (US) | 2021-06-24 | — | — | US | disclosed |
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | UNIV CALIFORNIA (US) | 2021-06-24 | — | — | US | disclosed |
| EP-3717450-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | The Regents of the University of California (US) | 2020-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | HGF, CXCL12, CCL11 | CSNK2A1 3987/4885CSNK2A2 3867/4885CSNK2B 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.