Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492821 | 0.81 | CSNK2A1 (0.49) | CSNK2A1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL22492839 | 0.81 | CSNK2A1 (0.49) | CSNK2A1NPC1RAB9ACCNA2CDK2 | |
| SCHEMBL2798077 | 0.77 | ALDH1A1 (0.50) | MAPTRAB9AALDH1A1PTPN11L3MBTL1 | |
| SCHEMBL22492805 | 0.75 | CDK2 (0.57) | CSNK2A1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL22492833 | 0.75 | SIRT2 (0.48) | MAPTNPC1RAB9ACCNA2CDK2 | |
| SCHEMBL22492801 | 0.74 | MAPT (0.59) | CSNK2A1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL22492828 | 0.71 | CCNA2 (0.52) | CSNK2A1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL22492764 | 0.70 | RAB9A (0.52) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL16346233 | 0.69 | ACACB (0.50) | GRM5NPC1RAB9AALDH1A1ALK | |
| SCHEMBL26988072 | 0.68 | LMNA (0.40) | MAPTRAB9AALDH1A1ALKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | UNIV CALIFORNIA (US) | 2021-06-24 | — | — | US | disclosed |
| EP-3717450-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | The Regents of the University of California (US) | 2020-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | HGF, CXCL12, CCL11 | CSNK2A1 3987/4885GRM5 3579/4885MAPT 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.