Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22500876 | 0.79 | SLC6A4 (0.38) | GABRR1SLC6A4 | |
| SCHEMBL22493943 | 0.79 | SLC6A4 (0.38) | GABRR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL22493932 | 0.78 | SLC6A4 (0.37) | GABRR1SLC6A4 | |
| SCHEMBL301120 | 0.65 | — | — | |
| SCHEMBL1173556 | 0.65 | — | — | |
| SCHEMBL12473695 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL11821301 | 0.63 | — | — | |
| Bromide SCHEMBL11824101 | 0.63 | — | — | |
| SCHEMBL22519005 | 0.63 | CHRNB2 (0.36) | SLC6A4 | |
| SCHEMBL24868049 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078153-B2 | 2-difluoro substituted 4-aminocyclopentanecarboxylic acids as inhibitors of gamma-aminobutyric acid aminotransferase and human ornithine aminotransferase | NORTHWESTERN UNIVERSITY (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200317606-A1 | 2-DIFLUORO SUBSTITUTED 4-AMINOCYCLOPENTANECARBOXYLIC ACIDS AS INHIBITORS OF GAMMA-AMINOBUTYRIC ACID AMINOTRANSFERASE AND HUMAN ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078153-B2 | 2-difluoro substituted 4-aminocyclopentanecarboxylic acids as inhibitors of gamma-aminobutyric acid aminotransferase and human ornithine aminotransferase | OAT, OTC, SLC6A13 | GABRR1 53/4885SLC6A4 226/4885 |
| US-20200317606-A1 | 2-DIFLUORO SUBSTITUTED 4-AMINOCYCLOPENTANECARBOXYLIC ACIDS AS INHIBITORS OF GAMMA-AMINOBUTYRIC ACID AMINOTRANSFERASE AND HUMAN ORNITHINE AMINOTRANSFERASE | OAT, OTC, SLC6A13 | GABRR1 53/4885SLC6A4 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.