Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494086 | 1.00 | FAAH (0.65) | FAAHLMNAEPHX2POLBKMT2A | |
| SCHEMBL22494084 | 1.00 | FAAH (0.65) | FAAHLMNAEPHX2POLBKMT2A | |
| SCHEMBL22525299 | 0.89 | EPHX2 (0.55) | FAAHLMNAEPHX2 | |
| SCHEMBL6121330 | 0.88 | LMNA (0.74) | FAAHLMNAEPHX2POLBKMT2A | |
| SCHEMBL28378099 | 0.85 | FAAH (0.64) | FAAHEPHX2 | |
| SCHEMBL31511860 | 0.85 | FAAH (0.64) | FAAHEPHX2 | |
| SCHEMBL22494108 | 0.83 | FAAH (0.91) | FAAHEPHX2 | |
| SCHEMBL22494099 | 0.83 | FAAH (0.91) | FAAHEPHX2 | |
| SCHEMBL22494087 | 0.83 | FAAH (0.91) | FAAHEPHX2 | |
| SCHEMBL22494089 | 0.83 | FAAH (0.91) | FAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-21 | — | — | US | disclosed |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | PC, UQCRC1, SQOR | FAAH 1063/4885LMNA 3926/4885EPHX2 1255/4885 |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | PC, UQCRC1, SQOR | FAAH 1063/4885LMNA 3926/4885EPHX2 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.