Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16279951 | 0.89 | KDM4E (0.37) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL16280403 | 0.85 | ALDH1A1 (0.35) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL274692 | 0.85 | NPC1 (0.57) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31388010 | 0.84 | MAPK14 (0.48) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL1012452 | 0.84 | MAPK14 (0.48) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL1014042 | 0.84 | CYP11B2 (0.39) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28700813 | 0.83 | MAPK14 (0.47) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL31265748 | 0.80 | LMNA (0.37) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31388019 | 0.79 | TRPV1 (0.42) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL12982424 | 0.79 | TRPV1 (0.37) | GRNSORT1CDK8MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490458-A | C-3 pyrazole substituted indazole derivative and application thereof | 沈阳药科大学 | 2025-02-21 | — | — | CN | disclosed |
| WO-2025035645-A1 | C-3 PYRAZOLE SUBSTITUTED INDAZOLE DERIVATIVE AND USE THEREOF | 沈阳药科大学 | 2025-02-20 | — | — | WO | disclosed |
| US-20110195110-A1 | UREA COMPOUNDS USEFUL IN THE TREATMENT OF CANCER | BAYER HEALTHCARE LLC | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195110-A1 | UREA COMPOUNDS USEFUL IN THE TREATMENT OF CANCER | UMPS, SLC14A1, CPS1 | KDM4E 2020/4885NPC1 1587/4885RAB9A 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.