SCHEMBL22503302

SCHEMBL22503302

C=Cc1cccc(CC(=O)NS(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EGFR P00533 6/20 0.41
ERBB2 P04626 6/20 0.41
PTGS1 P23219 1/20 0.41
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP12 P39900 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
FAAH O00519 1/20 0.37
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22503066 0.85 PTGS1 (0.39) EGFRERBB2PTGS1MMP2MMP9
SCHEMBL22503071 0.83 EGFR (0.43) EGFRERBB2PTGS1MMP2MMP9
SCHEMBL26163042 0.78 EGFR (0.53) EGFRERBB2MMP2MMP9MMP12
SCHEMBL15840358 0.78 CYP19A1 (0.47) PTGS1FAAH
SCHEMBL22503065 0.74 PTGS1 (0.38) EGFRERBB2PTGS1MMP2MMP9
SCHEMBL19480403 0.73 FAAH (0.32) FAAH
SCHEMBL7597396 0.73 PRMT1 (0.64) MEN1KMT2AMAPTFAAHPOLB
SCHEMBL22503318 0.73 THRB (0.40) EGFRERBB2PTGS1MMP2MMP9
SCHEMBL22503198 0.73 MMP2 (0.43) EGFRERBB2PTGS1MMP2MMP9
SCHEMBL7597392 0.72 MEN1 (0.45) MEN1KMT2AMAPTFAAHPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-10792489-B2 Bio-electrode composition, bio-electrode, and method for manufacturing the bio-electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-06 US disclosed