SCHEMBL19480403

SCHEMBL19480403

C=Cc1cccc(COS(=O)(=O)NS(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
CA2 P00918 2/20 0.31
PTPN1 P18031 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19480398 0.85 RAB9A (0.33) CA2
SCHEMBL18195854 0.79 CA2 (0.49) FAAHCA2
SCHEMBL19480396 0.79 CYSLTR2 (0.30)
SCHEMBL19480422 0.78 LMNA (0.33)
SCHEMBL19480423 0.77 USP2 (0.36) FAAHTDP1
SCHEMBL15840358 0.77 CYP19A1 (0.47) FAAHCYP4F2CYP4A11TP53TDP1
SCHEMBL19480419 0.76 POLB (0.33)
SCHEMBL22503302 0.73 EGFR (0.41) FAAH
SCHEMBL26230041 0.72 CA2 (0.40) TP53TDP1CA2
SCHEMBL24465280 0.71 ALDH1A1 (0.49) CYP4F2CYP4A11TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170299963-A1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170299963-A1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS ASIC1, PKD1, ARCN1 FAAH 4552/4885CYP4F2 4735/4885CYP4A11 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.