SCHEMBL2250804

SCHEMBL2250804

CC(=CC12CC3CC(CC(C3)C1)C2)C(=O)OO

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
EPHX1 P07099 2/20 0.33
GLA P06280 1/20 0.33
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
EPHX2 P34913 2/20 0.31
NPFFR1 Q9GZQ6 1/20 0.31
NPFFR2 Q9Y5X5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702221 0.85 GLA (0.40) ALDH1A1EPHX1GLAMEN1KMT2A
SCHEMBL7125894 0.85 GLA (0.40) ALDH1A1EPHX1GLAMEN1KMT2A
SCHEMBL15348321 0.82 NAAA (0.36) ALDH1A1EPHX1GLATHRBCYP2C9
SCHEMBL14973423 0.81 EPHX2 (0.35) ALDH1A1EPHX1EPHX2
SCHEMBL25401545 0.81 LMNA (0.43) ALDH1A1CYP2C9MEN1KMT2AEPHX2
SCHEMBL157720 0.79 THRB (0.39) ALDH1A1EPHX1GLATHRBCYP2C9
SCHEMBL757168 0.79 THRB (0.39) ALDH1A1EPHX1GLATHRBCYP2C9
SCHEMBL3828264 0.78 ALDH1A1 (0.36) ALDH1A1GLATHRBMEN1KMT2A
SCHEMBL562688 0.77 THRB (0.38) ALDH1A1EPHX1GLATHRBCYP2C9
SCHEMBL4084702 0.77 NPFFR1 (0.40) ALDH1A1EPHX1THRBCYP2C9EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8491965-B2 Method of controlling orientation of domains in block copolymer films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-07-23 US claimed
US-20090181171-A1 Method of Controlling Orientation of Domains in Block Copolymer Films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US claimed
US-8491965-B2 Method of controlling orientation of domains in block copolymer films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-07-23 US disclosed
US-7989026-B2 Method of use of epoxy-containing cycloaliphatic acrylic polymers as orientation control layers for block copolymer thin films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-08-02 US disclosed
US-7763319-B2 Coating a substrated with a solution of both a styrene-methyl methacrylate block polymer and a homo- or copolymer of epoxycyclopentadienyl (meth)acrylate that has an affinity for the substrate that is greater than that of the block polymer and baking; the polymers segregate into layers; etching INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-07-27 US disclosed
US-20090181171-A1 Method of Controlling Orientation of Domains in Block Copolymer Films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US disclosed
US-20090182093-A1 Coating a substrated with a solution of both a styrene-methyl methacrylate block polymer and a homo- or copolymer of epoxycyclopentadienyl (meth)acrylate that has an affinity for the substrate that is greater than that of the block polymer and baking; the polymers segregate into layers; etching INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US disclosed
US-20090179001-A1 METHOD OF USE OF EPOXY-CONTAINING CYCLOALIPHATIC ACRYLIC POLYMERS AS ORIENTATION CONTROL LAYERS FOR BLOCK COPOLYMER THIN FILMS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US disclosed
US-7189491-B2 Photoresist composition for deep UV and process thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2007-03-13 US disclosed
EP-1709485-A2 PHOTORESIST COMPOSITION FOR DEEP UV AND PROCESS THEREOF AZ Electronic Materials USA Corp. (US) 2006-10-11 EP disclosed
WO-2005059652-A2 PHOTORESIST COMPOSITION FOR DEEP UV AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2005-06-30 WO disclosed
US-20050130058-A1 Photoresist composition for deep UV and process thereof MERCK PATENT GMBH (DE) 2005-06-16 US disclosed