SCHEMBL7125894

SCHEMBL7125894

COC(=O)/C(C)=C/C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.40
ALDH1A1 P00352 4/20 0.37
EPHX1 P07099 2/20 0.36
EPHX2 P34913 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TSHR P16473 1/20 0.35
CNR2 P34972 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702221 1.00 GLA (0.40) GLAALDH1A1EPHX1EPHX2MEN1
SCHEMBL2250804 0.85 ALDH1A1 (0.33) GLAALDH1A1EPHX1EPHX2MEN1
SCHEMBL701445 0.85 PKM (0.36) GLAALDH1A1EPHX1TSHRCNR2
SCHEMBL6905424 0.82
SCHEMBL15348321 0.82 NAAA (0.36) GLAALDH1A1EPHX1EPHX2MEN1
SCHEMBL3828264 0.82 ALDH1A1 (0.36) GLAALDH1A1EPHX2MEN1KMT2A
SCHEMBL25401545 0.81 LMNA (0.43) ALDH1A1EPHX2MEN1KMT2ACNR2
SCHEMBL14973423 0.81 EPHX2 (0.35) ALDH1A1EPHX1EPHX2TSHR
SCHEMBL157720 0.79 THRB (0.39) GLAALDH1A1EPHX1EPHX2
SCHEMBL757168 0.79 THRB (0.39) GLAALDH1A1EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664022-B1 Forming relief image on substrate by coating with amplified positive resin and iodinium or sulfonium compound comprising naphthyl, thienyl or pentafluorophenyl substituents; exposure to patterned activating radiation; development SHIPLEY COMPANY, L.L.C. 2003-12-16 US disclosed
WO-2002019033-A2 PHOTOACID GENERATORS AND PHOTORESISTS COMPRISING SAME SHIPLEY COMPANY, L.L.C. (US) 2002-03-07 WO disclosed