Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24513016 | 0.81 | MEN1 (0.43) | RORARORCRORBMAOBGRIK1 | |
| SCHEMBL22479058 | 0.81 | GRIK1 (0.37) | RORARORCRORBMAOBGRIK1 | |
| SCHEMBL9613205 | 0.75 | GPR35 (0.57) | CYP1A2 | |
| SCHEMBL13881352 | 0.75 | GPR35 (0.43) | RORARORCRORBMAOBLMNA | |
| SCHEMBL22368580 | 0.73 | HTR2A (0.42) | MTNR1AMTNR1BLMNACYP1A2 | |
| SCHEMBL13084772 | 0.73 | RORC (0.54) | RORARORCRORBLMNA | |
| SCHEMBL27412938 | 0.72 | RORA (0.41) | RORARORCRORBCASRLMNA | |
| SCHEMBL19546070 | 0.69 | RORA (0.40) | RORARORCRORBMAOBLMNA | |
| SCHEMBL15701642 | 0.69 | CYP19A1 (0.52) | RORCMTNR1AMTNR1B | |
| SCHEMBL11534871 | 0.69 | KDM4E (0.60) | LMNACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205467-A1 | STAT3 PROTEIN DEGRADERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-10-08 | — | — | WO | disclosed |