Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479058 | 0.87 | GRIK1 (0.37) | RORARORCRORBCASRALDH1A1 | |
| SCHEMBL19531667 | 0.80 | POLB (0.42) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL21730433 | 0.78 | LMNA (0.35) | RORARORCRORBALDH1A1KDM4E | |
| SCHEMBL13921917 | 0.76 | RORA (0.58) | RORARORCRORBALDH1A1KDM4E | |
| SCHEMBL24513016 | 0.73 | MEN1 (0.43) | RORARORCRORBALDH1A1KDM4E | |
| SCHEMBL20646947 | 0.73 | PSEN1 (0.45) | RORARORCRORBCASRALDH1A1 | |
| SCHEMBL22515646 | 0.72 | RORA (0.36) | RORARORCRORBCASRGAA | |
| SCHEMBL11527429 | 0.72 | KMT2A (0.48) | RORARORCRORBKDM4EGAA | |
| SCHEMBL12827380 | 0.71 | AKR1C3 (0.42) | RORARORCRORBALDH1A1KDM4E | |
| SCHEMBL9613205 | 0.71 | GPR35 (0.57) | ALDH1A1KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097099-B1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO INC (US) | 2024-06-26 | — | — | EP | disclosed |