Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478677 | 0.85 | DRD2 (0.41) | DRD2DRD3TLR9TLR8TLR7 | |
| SCHEMBL20883545 | 0.84 | TLR9 (0.44) | DRD2DRD3TLR9TLR8TLR7 | |
| SCHEMBL22542119 | 0.82 | SLC18A3 (0.48) | DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL14924437 | 0.78 | SLC6A2 (0.42) | DRD2DRD4SLC6A4HTR2A | |
| SCHEMBL10196678 | 0.77 | DRD2 (0.50) | DRD2DRD4DRD3TLR9TLR8 | |
| SCHEMBL22547351 | 0.77 | SIGMAR1 (0.44) | DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL22542109 | 0.77 | HTR1A (0.43) | DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL22542116 | 0.75 | DRD4 (0.45) | DRD2DRD4DRD3 | |
| SCHEMBL8289625 | 0.74 | CHRNB2 (0.41) | SLC6A4 | |
| SCHEMBL22542097 | 0.74 | DRD2 (0.38) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210383-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020210377-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |