Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22545154 | 0.90 | TK1 (0.38) | TK1 | |
| SCHEMBL21580550 | 0.89 | — | — | |
| SCHEMBL13909169 | 0.79 | — | — | |
| SCHEMBL3077135 | 0.78 | TK1 (0.48) | TK1 | |
| SCHEMBL15725694 | 0.78 | — | — | |
| SCHEMBL20707130 | 0.77 | — | — | |
| SCHEMBL22598325 | 0.75 | POLB (0.49) | — | |
| SCHEMBL25469637 | 0.72 | — | — | |
| SCHEMBL8049881 | 0.71 | POLB (0.51) | — | |
| SCHEMBL2301090 | 0.70 | POLB (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008359-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-18 | — | — | US | disclosed |
| US-20200325167-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325167-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | TK1 22/4885 |
| US-11008359-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TK1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.