Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262342 | 1.00 | CASP1 (0.36) | CASP1CASP7HSD17B10OPRK1KDM4E | |
| SCHEMBL30938756 | 1.00 | CASP1 (0.36) | CASP1CASP7HSD17B10OPRK1KDM4E | |
| SCHEMBL22527697 | 0.87 | GLP1R (0.33) | — | |
| SCHEMBL22527698 | 0.87 | GLP1R (0.33) | — | |
| SCHEMBL30938745 | 0.85 | ALDH1A1 (0.42) | OPRK1KDM4EALDH1A1GAATP53 | |
| SCHEMBL29262336 | 0.85 | ALDH1A1 (0.42) | OPRK1KDM4EALDH1A1GAATP53 | |
| SCHEMBL22550750 | 0.85 | ALDH1A1 (0.42) | OPRK1KDM4EALDH1A1GAATP53 | |
| SCHEMBL22392029 | 0.81 | KCNH2 (0.38) | CASP1CASP7HSD17B10OPRK1KDM4E | |
| SCHEMBL22392052 | 0.79 | CASP1 (0.40) | CASP1CASP7HSD17B10OPRK1KDM4E | |
| SCHEMBL30938765 | 0.79 | CASP1 (0.40) | CASP1CASP7HSD17B10OPRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042883-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2025-02-06 | — | — | US | disclosed |
| CN-113853371-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20230278991-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2023-09-07 | — | — | US | disclosed |
| US-20230278991-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2023-09-07 | — | — | US | disclosed |
| US-20230278991-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2023-09-07 | — | — | US | disclosed |
| US-11591321-B2 | GLP-1R agonists and uses thereof | QILU REGOR THERAPEUTICS INC. (CN) | 2023-02-28 | — | — | US | disclosed |
| EP-3953344-A1 | GLP-IR AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2022-02-16 | — | — | EP | disclosed |
| US-20210179594-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2021-06-17 | — | — | US | disclosed |
| US-10954221-B2 | GLP-1R agonists and uses thereof | QILU REGOR THERAPEUTICS INC. (CN) | 2021-03-23 | — | — | US | disclosed |
| US-20200325121-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591321-B2 | GLP-1R agonists and uses thereof | GLP1R, GPR119, GIPR | CASP1 2274/4885CASP7 1701/4885HSD17B10 420/4885 |
| US-10954221-B2 | GLP-1R agonists and uses thereof | GLP1R, GPR119, GIPR | CASP1 1919/4885CASP7 1769/4885HSD17B10 415/4885 |
| US-20230278991-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | CASP1 1919/4885CASP7 1769/4885HSD17B10 415/4885 |
| US-20250042883-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | CASP1 1919/4885CASP7 1769/4885HSD17B10 415/4885 |
| US-20200325121-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | CASP1 1919/4885CASP7 1769/4885HSD17B10 415/4885 |
| US-20210179594-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | CASP1 1919/4885CASP7 1769/4885HSD17B10 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.