Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262336 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL22550750 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL22527875 | 0.91 | THRB (0.38) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL22527873 | 0.91 | THRB (0.38) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL22550751 | 0.85 | CASP1 (0.36) | ALDH1A1LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL30938756 | 0.85 | CASP1 (0.36) | ALDH1A1LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL29262342 | 0.85 | CASP1 (0.36) | ALDH1A1LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL22391742 | 0.83 | LMNA (0.44) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL24401162 | 0.81 | ADORA1 (0.39) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL24401166 | 0.78 | ADORA1 (0.39) | ALDH1A1LMNAMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113853371-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-05-03 | — | — | CN | disclosed |