Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552942 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22552897 | 0.84 | MEN1 (0.38) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22552896 | 0.84 | MEN1 (0.38) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22552661 | 0.84 | MEN1 (0.38) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22552663 | 0.84 | MEN1 (0.38) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL20825675 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22580075 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL113192 | 0.79 | OPRK1 (0.40) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22579993 | 0.76 | — | — | |
| SCHEMBL28380069 | 0.76 | KMT2A (0.39) | ALDH1A1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681875-B1 | CYCLIC PEPTIDE ANTIBIOTICS | HOFFMANN LA ROCHE (CH) | 2026-01-14 | — | — | EP | disclosed |
| US-11279735-B2 | Cyclic peptide antibiotics | GENENTECH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200331968-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-10-22 | — | — | US | disclosed |
| CN-111148739-A | Cyclopeptide antibiotics | 豪夫迈·罗氏有限公司 | 2020-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331968-A1 | CYCLIC PEPTIDE ANTIBIOTICS | NPPA, LNPEP, CLPP | ALDH1A1 4279/4885MEN1 4359/4885NPC1 1580/4885 |
| US-11279735-B2 | Cyclic peptide antibiotics | NPPA, LNPEP, CLPP | ALDH1A1 4279/4885MEN1 4359/4885NPC1 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.