SCHEMBL22554795

SCHEMBL22554795

Cc1cccc(C)c1-c1cc(-c2ccc(-c3ccccc3)cc2)ccc1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
TSHR P16473 1/20 0.47
MAOA P21397 1/20 0.45
HSD17B10 Q99714 3/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 3/20 0.44
GAA P10253 3/20 0.44
HPGD P15428 3/20 0.44
MEN1 O00255 2/20 0.44
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
USP2 O75604 1/20 0.44
HSP90AA1 P07900 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
TYMS P04818 1/20 0.43
IKBKB O14920 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22517368 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1TSHRMAOA
SCHEMBL30683153 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1TSHRMAOA
SCHEMBL30683143 0.85 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1TSHRMAOA
SCHEMBL16135148 0.85 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1TSHRMAOA
SCHEMBL22567857 0.85 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1TSHRMAOA
SCHEMBL55383 0.84 HSD17B10 (0.46) ALDH1A1CYP3A4TDP1TSHRMAOA
SCHEMBL20851654 0.82 ALDH1A1 (0.56) ALDH1A1CYP3A4TDP1MAOAHSD17B10
SCHEMBL12286029 0.80 HSD17B10 (0.54) ALDH1A1CYP3A4TDP1MAOAHSD17B10
SCHEMBL30266735 0.80 MAOA (0.52) ALDH1A1CYP3A4TDP1MAOAHSD17B10
SCHEMBL22567844 0.80 ALDH1A1 (0.58) ALDH1A1CYP3A4TDP1MAOAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844270-B2 Compound and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-20200335698-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2020-10-22 US disclosed
US-20200335698-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2020-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844270-B2 Compound and organic light emitting device including the same TMEM109, CRY1, VDAC1 ALDH1A1 54/4885CYP3A4 212/4885TDP1 1190/4885
US-20200335698-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE TMEM109, TRPC1, MAP1LC3B ALDH1A1 155/4885CYP3A4 436/4885TDP1 1643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.