Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121635 | 1.00 | ADRA2C (0.34) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL1387795 | 0.77 | MAPT (0.39) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL4942075 | 0.71 | LMNA (0.34) | LMNATP53CYP1A2CYP3A4MAPT | |
| SCHEMBL25171318 | 0.66 | LMNA (0.54) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL70993 | 0.66 | LMNA (0.54) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL29370508 | 0.66 | LMNA (0.54) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL132630 | 0.65 | ALDH1A1 (0.55) | LMNACYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL31121633 | 0.65 | BRD4 (0.30) | — | |
| SCHEMBL22557695 | 0.65 | BRD4 (0.30) | — | |
| SCHEMBL6921270 | 0.65 | MAPT (0.42) | ADRA2CPTGS2HRH1HTR3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956334-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2025-09-24 | — | — | EP | disclosed |
| US-20230084690-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2023-03-16 | — | — | US | disclosed |
| EP-3956334-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2022-02-23 | — | — | EP | disclosed |
| CN-113692407-A | Compounds for optically active devices | 默克专利股份有限公司 | 2021-11-23 | — | — | CN | disclosed |
| WO-2020212543-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230084690-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | ADRA2C 3743/4885PTGS2 303/4885HRH1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.