Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 11/20 | 0.37 |
| ▸ | NPC1 | O15118 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167151 | 0.83 | KCNH3 (0.43) | CASP1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL3685659 | 0.82 | CASP1 (0.54) | CASP1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL28563216 | 0.76 | RAB9A (0.66) | RAB9ANPC1MAPTALDH1A1JAK2 | |
| SCHEMBL10727606 | 0.71 | CASP1 (0.42) | CASP1L3MBTL1LMNAHTTHSD17B10 | |
| SCHEMBL9910 | 0.71 | ALDH1A1 (0.40) | CASP1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL593132 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNA | |
| SCHEMBL25422725 | 0.69 | ALDH1A1 (0.42) | CASP1RAB9AMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11061003 | 0.69 | ALDH1A1 (0.39) | CASP1RAB9AMAPTALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28937474 | 0.69 | ALDH1A1 (0.39) | CASP1MAPTALDH1A1POLBLMNA | |
| SCHEMBL11394714 | 0.69 | ALDH1A1 (0.39) | CASP1RAB9AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207926-A1 | NOVEL DIHYDROTRIAZINE DERIVATIVE | HAMARI CHEMICALS, LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207926-A1 | NOVEL DIHYDROTRIAZINE DERIVATIVE | QDPR, DRD4, DRD1 | CASP1 146/4885RAB9A 2118/4885NPC1 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.