SCHEMBL22562468

SCHEMBL22562468

FC(F)(F)c1cc(-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)c(-c2cccc(-c3ccccc3)n2)c(-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KIF11 P52732 1/20 0.36
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPV3 Q8NET8 6/20 0.35
CTSS P25774 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NR3C1 P04150 1/20 0.34
PGR P06401 1/20 0.34
CYP11B2 P19099 1/20 0.34
TOP1 P11387 1/20 0.34
CCNE2 O96020 1/20 0.34
CDK4 P11802 1/20 0.34
CCND1 P24385 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22562470 0.97 RAB9A (0.36) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562392 0.95 ICMT (0.37) RAB9AMEN1KMT2ANPC1MAPT
SCHEMBL22562234 0.94 MAPT (0.38) RAB9AMEN1KMT2AMAPTTDP1
SCHEMBL22562483 0.92 CTSS (0.39) KIF11CTSSDGAT1KCNH2PDK2
SCHEMBL22562406 0.92 RAB9A (0.39) RAB9AMEN1KMT2ANPC1MAPT
SCHEMBL22562474 0.91 GSK3B (0.35) RAB9AMEN1KMT2AMAPTTRPV3
SCHEMBL22562469 0.91 RAB9A (0.38) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562609 0.90 RAB9A (0.36) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562305 0.90 ALDH1A3 (0.43) CTSSPDK2
SCHEMBL22562228 0.90 ENPP1 (0.38) KMT2ANR3C1PDK2MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3418278-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed