SCHEMBL22562469

SCHEMBL22562469

FC(F)(F)c1cc(-n2c3cc(-c4ccccc4)ccc3c3ccc(-c4ccccc4)cc32)c(-c2cccc(-c3ccccc3)n2)c(-n2c3cc(-c4ccccc4)ccc3c3ccc(-c4ccccc4)cc32)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KIF11 P52732 1/20 0.36
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPV3 Q8NET8 6/20 0.35
CTSS P25774 1/20 0.34
METAP2 P50579 1/20 0.34
CYP11B2 P19099 1/20 0.34
TOP1 P11387 1/20 0.34
MAT2A P31153 1/20 0.34
DHODH Q02127 1/20 0.34
DGAT1 O75907 1/20 0.33
KCNH2 Q12809 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22562609 0.97 RAB9A (0.36) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562227 0.92 MAPT (0.36) MEN1KMT2AKIF11MAPTDHODH
SCHEMBL22562405 0.92 MAT2A (0.41) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562404 0.91 PDK2 (0.34) RAB9AMEN1KMT2AMAPTTRPV3
SCHEMBL22562468 0.91 RAB9A (0.38) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562470 0.90 RAB9A (0.36) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562485 0.89 CTSS (0.38) CTSSMAT2APDK2
SCHEMBL22562230 0.88 RAB9A (0.36) RAB9AMEN1KMT2AKIF11NPC1
SCHEMBL22562388 0.88 L3MBTL1 (0.33) RAB9AMEN1KMT2AMAPTTRPV3
SCHEMBL22158665 0.87 CYP11B2 (0.39) RAB9AMEN1KMT2ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3418278-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed