SCHEMBL22562479

SCHEMBL22562479

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C#N)cc5)cc4n(-c4cc(C(F)(F)F)cc(-n5c6cc(-c7ccc(C#N)cc7)ccc6c6ccc(-c7ccc(C#N)cc7)cc65)c4-c4cccc(-c5ccccc5)n4)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 2/20 0.37
CTSS P25774 1/20 0.36
PDK2 Q15119 1/20 0.36
MYC P01106 1/20 0.35
KIF11 P52732 1/20 0.35
GABRA1 P14867 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
PPARG P37231 1/20 0.34
NCOA2 Q15596 1/20 0.34
NCOA1 Q15788 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
SYK P43405 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22562278 0.91 ALDH1A3 (0.41) ALDH1A3MYCGABRA1GABRG2GABRB3
SCHEMBL22562227 0.90 MAPT (0.36) ALDH1A3PDK2KIF11KDM4EHPGD
SCHEMBL22562485 0.89 CTSS (0.38) ALDH1A3CTSSPDK2MYCGABRA1
SCHEMBL22562574 0.89 CTSS (0.41) ALDH1A3CTSSPDK2GABRA1GABRG2
SCHEMBL22562483 0.88 CTSS (0.39) ALDH1A3CTSSPDK2MYCKIF11
SCHEMBL22562469 0.87 RAB9A (0.38) CTSSPDK2KIF11MAPTMAT2A
SCHEMBL22562440 0.87 ALDH1A3 (0.41) ALDH1A3CTSSPDK2GABRA1GABRG2
SCHEMBL22562304 0.87 CTSS (0.37) ALDH1A3CTSSPDK2MYCKIF11
SCHEMBL22562572 0.86 CTSS (0.39) ALDH1A3CTSSPDK2GABRA1GABRG2
SCHEMBL22562230 0.85 RAB9A (0.36) CTSSKIF11GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3418278-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed