SCHEMBL22562491

SCHEMBL22562491

FC(F)(F)c1cc(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c(-c2cccc(-c3ccccc3)n2)cc1-n1c2ccccc2c2cc(-c3ccccc3)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 2/20 0.38
MEN1 O00255 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
ACHE P22303 6/20 0.34
TSPO P30536 1/20 0.32
CYP11B1 P15538 1/20 0.32
NT5E P21589 1/20 0.32
USP1 O94782 1/20 0.32
WDR48 Q8TAF3 1/20 0.32
TRPA1 O75762 1/20 0.32
PIM1 P11309 2/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
DHODH Q02127 1/20 0.31
CDK4 P11802 2/20 0.31
ESR1 P03372 1/20 0.31
CCNE2 O96020 1/20 0.31
CCND1 P24385 1/20 0.31
CCNE1 P24864 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22562496 0.97 CYP11B2 (0.40) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562329 0.93 CYP11B2 (0.36) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562292 0.93 CYP11B2 (0.39) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562421 0.92 MAPT (0.39) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562490 0.91 KIF11 (0.36) CYP11B2MEN1RAB9AKMT2APIM1
SCHEMBL22562306 0.91 CYP11B2 (0.35) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562492 0.90 CYP11B2 (0.40) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562323 0.90 ALDH1A3 (0.35) CYP11B2HPGD
SCHEMBL22562601 0.90 PTGDR2 (0.35) CYP11B2MEN1RAB9AKMT2AACHE
SCHEMBL22562287 0.89 CYP11B2 (0.38) CYP11B2MEN1RAB9AKMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3418278-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed