SCHEMBL22562553

SCHEMBL22562553

FC(F)(F)c1ccc(-c2ccc3c4ccc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)cc4n(-c4cc(-c5cccc(-c6ccccc6)n5)cc(-n5c6cc(-c7ccc(C(F)(F)F)cc7C(F)(F)F)ccc6c6ccc(-c7ccc(C(F)(F)F)cc7C(F)(F)F)cc65)c4C(F)(F)F)c3c2)c(C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
CYP2C9 P11712 2/20 0.38
SCN9A Q15858 1/20 0.38
EDNRB P24530 1/20 0.37
EDNRA P25101 1/20 0.37
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
CYP11B2 P19099 1/20 0.34
MAT2A P31153 2/20 0.34
TOP1 P11387 1/20 0.34
DHODH Q02127 1/20 0.34
TRPV3 Q8NET8 2/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTGER1 P34995 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22562557 0.92 ALOX5AP (0.39) ALOX5APFEN1CYP2C9SCN9AEDNRB
SCHEMBL22562222 0.91 ALOX5AP (0.37) ALOX5APFEN1CYP2C9SCN9AEDNRB
SCHEMBL22562528 0.89 CTSS (0.39) ALOX5APFEN1CYP2C9SCN9AEDNRB
SCHEMBL22562478 0.88 MAT2A (0.41) CYP2C9ADORA2AADORA1MAT2ADHODH
SCHEMBL22562461 0.88 ALOX5AP (0.39) ALOX5APFEN1CYP2C9SCN9AEDNRB
SCHEMBL22562450 0.86 ALOX5AP (0.37) ALOX5APFEN1CYP2C9SCN9AEDNRB
SCHEMBL22562477 0.85 KIF11 (0.44) CYP2C9ADORA2AADORA1MAT2ADHODH
SCHEMBL19942800 0.85 KIF11 (0.36) ALOX5APFEN1CYP2C9SCN9AEDNRB
SCHEMBL22562614 0.85 MEN1 (0.40) CYP2C9CYP11B2DHODHCYP1A2KDM4E
SCHEMBL22562453 0.82 MEN1 (0.37) CYP11B2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3418278-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed