Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563772 | 0.92 | KDM4E (0.34) | CACNA2D1KDM4EALDH1A1MAPT | |
| SCHEMBL22563775 | 0.89 | ALDH1A1 (0.31) | SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL22564161 | 0.89 | NR1H4 (0.37) | SMN1; SMN2CYP3A4PDE2AKDM4EALDH1A1 | |
| SCHEMBL22564364 | 0.88 | KMT2A (0.34) | SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL22564091 | 0.88 | NR1H4 (0.38) | CACNA2D1POLBKDM4EALDH1A1MAPT | |
| SCHEMBL22564153 | 0.87 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20902038 | 0.86 | NR1H4 (0.35) | CYP3A4PTGER1 | |
| SCHEMBL22563841 | 0.85 | NR1H4 (0.37) | CACNA2D1POLBKDM4EALDH1A1 | |
| SCHEMBL20844961 | 0.85 | P2RX7 (0.32) | KDM4EALDH1A1MAPT | |
| SCHEMBL20902007 | 0.83 | ALDH1A1 (0.41) | POLBCYP3A4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |