Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563773 | 0.92 | KLKB1 (0.32) | KDM4EALDH1A1MAPTCACNA2D1 | |
| SCHEMBL22564161 | 0.92 | NR1H4 (0.37) | KDM4EALDH1A1MAPTNR1H4FFAR1 | |
| SCHEMBL22563775 | 0.92 | ALDH1A1 (0.31) | KDM4EALDH1A1MAPTNR1H4 | |
| SCHEMBL22564364 | 0.92 | KMT2A (0.34) | KDM4EALDH1A1MAPTSGMS2 | |
| SCHEMBL22564091 | 0.91 | NR1H4 (0.38) | KDM4EALDH1A1MAPTNR1H4CACNA2D1 | |
| SCHEMBL22564153 | 0.91 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL20844961 | 0.88 | P2RX7 (0.32) | KDM4EALDH1A1MAPT | |
| SCHEMBL19909882 | 0.87 | NR1H4 (0.33) | ALDH1A1NR1H4 | |
| SCHEMBL20902007 | 0.87 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTNR1H4 | |
| SCHEMBL22563918 | 0.86 | SIGMAR1 (0.40) | KDM4EMAPTNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |