Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563940 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL22563832 | 0.86 | MCHR1 (0.35) | ADORA3ADORA2AADORA1MCHR1MEN1 | |
| SCHEMBL22564010 | 0.86 | ADORA3 (0.31) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22564079 | 0.84 | HTR2A (0.32) | ADORA3ADORA2AADORA1SMN1; SMN2LMNA | |
| SCHEMBL22564070 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TDP1SMN1; SMN2LMNAPOLB | |
| SCHEMBL18504096 | 0.84 | ALDH1A1 (0.37) | ALDH1A1ADRA2BPTGS1TDP1ADORA3 | |
| SCHEMBL22563931 | 0.84 | CYP3A4 (0.36) | TDP1ADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL22563827 | 0.84 | RXRA (0.32) | — | |
| SCHEMBL22564015 | 0.83 | L3MBTL1 (0.33) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL22564122 | 0.81 | KDM4E (0.32) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |