Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563897 | 0.88 | ALDH1A1 (0.37) | ALDH1A1ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL22564010 | 0.87 | ADORA3 (0.31) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22563832 | 0.85 | MCHR1 (0.35) | ADORA3ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL18504557 | 0.85 | ALDH1A1 (0.43) | ALDH1A1ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL22564306 | 0.85 | ALDH1A1 (0.32) | ALDH1A1ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL22564103 | 0.85 | L3MBTL1 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22564063 | 0.85 | ALDH1A1 (0.37) | ALDH1A1PKMPOLBL3MBTL1LMNA | |
| SCHEMBL22563935 | 0.83 | HTR1A (0.31) | PKM | |
| SCHEMBL22564474 | 0.83 | HTT (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22563931 | 0.83 | CYP3A4 (0.36) | ADORA3ADORA2AADORA1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |