Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563858 | 0.90 | TAS2R14 (0.35) | SMN1; SMN2KLKB1ALDH1A1LMNAHTT | |
| SCHEMBL22564535 | 0.89 | ROCK2 (0.34) | SMN1; SMN2KLKB1ALDH1A1LMNAHTT | |
| SCHEMBL22564212 | 0.89 | IRAK4 (0.36) | ALDH1A1LMNAMAPTTDP1HCRTR1 | |
| SCHEMBL18504984 | 0.88 | SMN1; SMN2 (0.34) | SMN1; SMN2KLKB1ALDH1A1LMNAHTT | |
| SCHEMBL22563951 | 0.87 | KLKB1 (0.36) | SMN1; SMN2KLKB1ALDH1A1LMNAHTT | |
| SCHEMBL22564099 | 0.87 | ALDH1A1 (0.35) | SMN1; SMN2KLKB1ALDH1A1LMNAHTT | |
| SCHEMBL22564365 | 0.87 | NR1H4 (0.30) | NR1H4 | |
| SCHEMBL22564292 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2KLKB1ALDH1A1LMNAHTT | |
| SCHEMBL22564307 | 0.85 | NPC1 (0.36) | SMN1; SMN2LMNAHTTMAPTMRGPRX4 | |
| SCHEMBL22564513 | 0.84 | L3MBTL1 (0.37) | LMNAHTTMAPTHCRTR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |