Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563858 | 0.90 | TAS2R14 (0.35) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL22564143 | 0.89 | IRAK4 (0.47) | JAK3IRAK4MEN1KMT2ATBXAS1 | |
| SCHEMBL22564366 | 0.89 | SMN1; SMN2 (0.34) | HTTSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL18504446 | 0.88 | ROCK2 (0.35) | ROCK2JAK3IRAK4MEN1KMT2A | |
| SCHEMBL22564099 | 0.87 | ALDH1A1 (0.35) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL22563951 | 0.87 | KLKB1 (0.36) | KMT2AHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL22564299 | 0.87 | KMT2A (0.34) | MEN1KMT2ATBXAS1HTTPARP1 | |
| SCHEMBL22564292 | 0.86 | SMN1; SMN2 (0.36) | HTTSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL22563984 | 0.85 | TBXAS1 (0.37) | TBXAS1HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL22564534 | 0.85 | LMNA (0.39) | JAK3MEN1KMT2ATBXAS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |