Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD2 | O14939 | 1/20 | 0.62 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494151 | 0.89 | OPRM1 (0.60) | SLC6A9SLC6A5OPRK1OPRL1OPRM1 | |
| SCHEMBL5244755 | 0.80 | PLD2 (0.62) | PLD2SLC6A9SLC6A5OPRK1OPRL1 | |
| SCHEMBL5553371 | 0.79 | CYP3A4 (0.61) | PLD2SLC6A9SLC6A5OPRK1OPRL1 | |
| SCHEMBL318707 | 0.77 | HSD17B10 (0.65) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL9225104 | 0.77 | OPRM1 (0.61) | SLC6A9SLC6A5OPRK1OPRL1OPRM1 | |
| SCHEMBL10311318 | 0.77 | PLD2 (1.00) | PLD2 | |
| SCHEMBL26330793 | 0.76 | OPRK1 (0.63) | OPRK1OPRL1OPRM1OPRD1HSD17B10 | |
| SCHEMBL5557913 | 0.76 | PLD2 (0.55) | PLD2SLC6A9SLC6A5OPRK1OPRL1 | |
| SCHEMBL5254961 | 0.75 | OPRK1 (0.62) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL21634299 | 0.75 | HSD17B10 (0.62) | SLC6A9OPRK1OPRL1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |