Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 10/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22597794 | 0.83 | PARP1 (0.41) | KDM4EALDH1A1KMT2A | |
| SCHEMBL22598044 | 0.81 | MAPT (0.39) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL22597760 | 0.73 | KMT2A (0.39) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL22597763 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1KMT2A | |
| SCHEMBL30811710 | 0.71 | KDM4E (0.70) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL28462165 | 0.70 | KDM4E (0.41) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL22598043 | 0.70 | HSD17B1 (0.35) | KDM4EMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL30811690 | 0.70 | KDM4E (0.68) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL18373951 | 0.70 | CHKA (0.37) | MEN1ALDH1A1KMT2A | |
| SCHEMBL22597814 | 0.69 | BCAT2 (0.41) | KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339555-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339555-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | MYD88, C3AR1, FCGRT | KDM4E 3983/4885MEN1 169/4885ALDH1A1 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.