Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 8/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811710 | 0.74 | KDM4E (0.70) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| Hydrochloric Acid SCHEMBL30811690 | 0.73 | KDM4E (0.68) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL30314856 | 0.73 | CHEK2 (0.58) | ARCHEK2CHEK1SIRT2SIRT3 | |
| SCHEMBL2932508 | 0.73 | CHEK2 (0.58) | ARCHEK2CHEK1SIRT2SIRT3 | |
| SCHEMBL28468737 | 0.72 | GRM5 (0.37) | KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL22597846 | 0.70 | KDM4E (0.38) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL2692918 | 0.68 | NNMT (0.36) | ALDH1A1CHEK2CHEK1SIRT6 | |
| SCHEMBL2841794 | 0.66 | SIRT2 (0.54) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL26099756 | 0.66 | FBP1 (0.36) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL9850025 | 0.66 | ALOX5 (0.46) | KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111629728-A | Compounds and methods for modulating adenosine A2B receptor and adenosine A2A receptor | 科尔沃斯制药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |