SCHEMBL226076

SCHEMBL226076

C=CC(=O)OCCc1cc(C)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.48
RAB9A P51151 8/20 0.48
POLB P06746 2/20 0.46
LMNA P02545 1/20 0.42
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 5/20 0.42
KDM4E B2RXH2 4/20 0.41
THRB P10828 2/20 0.40
MAPT P10636 5/20 0.39
HPGD P15428 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX5 P09917 3/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
AKR1B10 O60218 1/20 0.34
AKR1B1 P15121 1/20 0.34
IGF2BP2 Q9Y6M1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372447 1.00 NPC1 (0.48) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL29277521 0.95 NPC1 (0.44) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL7024606 0.90 NPC1 (0.43) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL28684325 0.89 NPC1 (0.50) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL17701290 0.88 NPC1 (0.38) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL29315729 0.87 NPC1 (0.49) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL4187360 0.86 THRB (0.38) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL7032209 0.86 NPC1 (0.42) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL31579004 0.86 THRB (0.41) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL27503098 0.85 THRB (0.38) NPC1RAB9APOLBLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7133450-A None JP disclosed
US-20260139087-A1 COMPOUND, POLYMER, LIGHT STABILIZER COMPOSITION, RESIN COMPOSITION, COATING MATERIAL COMPOSITION, ARTICLE, SEALING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING WEATHER-RESISTANT RESIN COMPOSITION, AND METHOD FOR IMPROVING WEATHER RESISTANCE OF SYNTHETIC RESIN ADEKA CORPORATION (JP) 2026-05-21 US disclosed
EP-4745198-A1 RESIN COMPOSITION, MOLDED ARTICLE, RESIN ADDITIVE COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, METHOD FOR IMPROVING CRYSTALLINITY OF CRYSTALLINE RESIN, AND MATERIAL FOR RESIN ADDITIVE COMPOSITION ADEKA CORPORATION (JP) 2026-05-20 EP disclosed
US-12577355-B2 Polyester polymer compositions CELANESE SALES GERMANY GMBH (DE) 2026-03-17 US disclosed
US-12577376-B2 Molded articles with laser-formed pattern Celanese Interntaional Corporation (US) 2026-03-17 US disclosed
US-20260002014-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2026-01-01 US disclosed
EP-3578161-B1 METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC ADEKA CORP (JP) 2025-11-12 EP disclosed
US-12466938-B2 Resin additive composition, thermoplastic resin composition, and molded article thereof ADEKA CORPORATION (JP) 2025-11-11 US disclosed
US-12435205-B2 Resin composition and molded article thereof ADEKA CORPORATION (JP) 2025-10-07 US disclosed
EP-4130197-B1 FLAME RETARDANT COMPOSITION, FLAME-RESISTANT SYNTHETIC RESIN COMPOSITION, AND MOLDED BODY ADEKA CORP (JP) 2025-10-01 EP disclosed
EP-1384749-A1 ULTRAVIOLET ABSORBER FOR SYNTHETIC RESIN AND SYNTHETIC RESIN COMPOSITION CONTAINING THE SAME Asahi Denka Kogyo K. K. (JP) 2004-01-28 EP disclosed
EP-1375582-A2 Nucleating agent and crystalline polymer composition containing the same Asahi Denka Co., Ltd. (JP) 2004-01-02 EP disclosed
US-20030236329-A1 Nucleating agent and crystalline polymer composition containing the same ASAHI DENKA CO., LTD. (JP) 2003-12-25 US disclosed
US-20030162870-A1 Flame-retardant resin composition ASAHI DENKA CO., LTD. (JP) 2003-08-28 US disclosed
US-20030125432-A1 Granular composite additive for polyolefin, process for producing the same, and polyolefin composition containing the same ADEKA CORPORATION (JP) 2003-07-03 US disclosed
EP-1304350-A1 Flame-retardant resin composition Asahi Denka Co., Ltd. (JP) 2003-04-23 EP disclosed
EP-1266932-A1 GRANULAR COMPOSITE ADDITIVE FOR POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND POLYOLEFIN COMPOSITION CONTAINING THE SAME ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2002-12-18 EP disclosed
US-6432875-B1 LOW MOLECULAR WEIGHT POLYESTER ASAHI DENKA KOGYO K.K. (JP) 2002-08-13 US disclosed
EP-0987122-A1 THERMAL RECORDING MATERIAL ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2000-03-22 EP disclosed
JP-H07133450-A STABILIZED THERMOSETTING SYNTHETIC RESIN COATING COMPOSITION ASAHI DENKA KOGYO KK 1995-05-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577376-B2 Molded articles with laser-formed pattern LAS1L, PIM2, YES1 NPC1 3955/4885RAB9A 4207/4885POLB 4449/4885
US-12577355-B2 Polyester polymer compositions SMCHD1, PWWP2B, USP30 NPC1 4460/4885RAB9A 2876/4885POLB 981/4885
US-20260002014-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF NXF1, NOP2, RTF1 NPC1 554/4885RAB9A 4015/4885POLB 1613/4885
US-20260139087-A1 COMPOUND, POLYMER, LIGHT STABILIZER COMPOSITION, RESIN COMPOSITION, COATING MATERIAL COMPOSITION, ARTICLE, SEALING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING WEATHER-RESISTANT RESIN COMPOSITION, AND METHOD FOR IMPROVING WEATHER RESISTANCE OF SYNTHETIC RESIN SEM1, RAD51, SUN2 NPC1 821/4885RAB9A 2000/4885POLB 1784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.