Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732752 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MBTPS1TSHRMEN1KMT2A | |
| SCHEMBL8217404 | 0.79 | PPARG (0.44) | KMT2AL3MBTL1PPARGPPARDPPARA | |
| SCHEMBL27623896 | 0.75 | DPP4 (0.36) | ALDH1A1GAA | |
| SCHEMBL1798916 | 0.74 | L3MBTL1 (0.42) | L3MBTL1PPARGPPARDPPARAHTR2C | |
| SCHEMBL4525149 | 0.74 | GRM2 (0.40) | MBTPS1L3MBTL1 | |
| SCHEMBL24577516 | 0.73 | DPP4 (0.37) | — | |
| SCHEMBL5654759 | 0.72 | DRD2 (0.38) | PPARGPPARDPPARAGPR119 | |
| Formic Acid SCHEMBL27903276 | 0.72 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1PPARGPPARD | |
| SCHEMBL13668663 | 0.72 | MC4R (0.37) | ALDH1A1GAA | |
| SCHEMBL15820250 | 0.71 | HSD11B1 (0.43) | KMT2AL3MBTL1HTR2CSLC6A4MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994326-B2 | For treatment of various forms of neurodegeneration, including that from stroke, Alzheimer's disease, Parkinson's disease, and Huntington's disease | NORTHWESTERN UNIVERSITY (US) | 2011-08-09 | — | — | US | disclosed |