Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258375 | 0.87 | SLC18A3 (0.40) | PPARGPPARDPPARATAAR1OPRM1 | |
| SCHEMBL1798916 | 0.86 | L3MBTL1 (0.42) | PPARGPPARDPPARAOPRM1L3MBTL1 | |
| SCHEMBL12363036 | 0.86 | TAAR1 (0.40) | PPARGPPARDPPARATAAR1OPRM1 | |
| SCHEMBL4525149 | 0.81 | GRM2 (0.40) | OPRM1SIGMAR1L3MBTL1 | |
| SCHEMBL14191955 | 0.81 | GPR119 (0.37) | PPARGPPARDPPARATAAR1OPRM1 | |
| Formic Acid SCHEMBL27903276 | 0.80 | L3MBTL1 (0.47) | PPARGPPARDPPARAOPRM1KMT2A | |
| SCHEMBL2260853 | 0.79 | ALDH1A1 (0.40) | PPARGPPARDPPARAKMT2AGPR119 | |
| SCHEMBL5042994 | 0.79 | SLC6A2 (0.53) | OPRM1SLC6A4SLC6A3 | |
| SCHEMBL4511972 | 0.78 | SIGMAR1 (0.45) | NPC1RAB9ASIGMAR1 | |
| SCHEMBL2257504 | 0.78 | TAAR1 (0.50) | TAAR1KMT2ASIGMAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042353-A1 | POTENT AND HIGHLY SELECTIVE HETEROAROMATIC INHIBITORS OF NEURONAL NITRIC OXIDE SYNTHASE | NORTHWESTERN UNIVERSITY (US) | 2008-04-10 | — | — | WO | disclosed |