Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GPX4 | P36969 | 1/20 | 0.31 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.31 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15248892 | 0.83 | BRD4 (0.41) | GRIA1GRIA3LMNARECQLL3MBTL1 | |
| SCHEMBL22609347 | 0.78 | NPSR1 (0.45) | MEN1KMT2AALDH1A1GPX4 | |
| SCHEMBL2131097 | 0.77 | GRIA1 (0.49) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL2807054 | 0.76 | LMNA (0.54) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL13815993 | 0.74 | GRIA1 (0.46) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL5424082 | 0.74 | L3MBTL1 (0.46) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL28206204 | 0.72 | GRIA1 (0.45) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL29187896 | 0.71 | GRIA1 (0.44) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL5451073 | 0.71 | GRIA1 (0.60) | GRIA1GRIA3LMNARECQLHCAR2 | |
| SCHEMBL28222270 | 0.70 | HCAR2 (0.36) | GRIA1GRIA3HCAR2TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | GRIA1 823/4885GRIA3 904/4885LMNA 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.