Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486383 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9HSD17B10COPS5 | |
| SCHEMBL23453721 | 0.84 | COPS5 (0.46) | ALDH1A1CYP1A2CYP2C9HSD17B10COPS5 | |
| SCHEMBL23486285 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9HSD17B10COPS5 | |
| SCHEMBL22609269 | 0.80 | ILK (0.47) | ALDH1A1KMT2ALMNAMAPTPKM | |
| SCHEMBL23453753 | 0.80 | SRD5A2 (0.54) | ALDH1A1CYP1A2CYP2C9HSD17B10PTGDR2 | |
| SCHEMBL23453701 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C9HSD17B10PRMT3 | |
| SCHEMBL22609275 | 0.70 | NPC1 (0.41) | ALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL22609331 | 0.69 | ILK (0.57) | ALDH1A1CYP1A2CYP2C9HSD17B10KMT2A | |
| SCHEMBL24101222 | 0.69 | KMT2A (0.46) | ALDH1A1CYP1A2CYP2C9HSD17B10KMT2A | |
| SCHEMBL22609307 | 0.69 | KMT2A (0.41) | KMT2ANR4A2P4HTMCTBP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | ALDH1A1 149/4885CYP1A2 99/4885CYP2C9 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.