Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566196 | 0.94 | TIPARP (0.34) | TIPARPNPY5RPDE7A | |
| SCHEMBL22612370 | 0.94 | TIPARP (0.34) | TIPARPNPY5RPDE7A | |
| SCHEMBL22612368 | 0.94 | TIPARP (0.34) | TIPARPNPY5RPDE7A | |
| SCHEMBL22612362 | 0.79 | GRM5 (0.36) | NPY5RPDE7A | |
| SCHEMBL22612365 | 0.79 | GRM5 (0.36) | NPY5RPDE7A | |
| SCHEMBL22622952 | 0.79 | ALDH1A1 (0.45) | — | |
| SCHEMBL22612357 | 0.77 | TIPARP (0.33) | TIPARP | |
| SCHEMBL22612360 | 0.77 | TIPARP (0.33) | TIPARP | |
| SCHEMBL29409163 | 0.77 | TIPARP (0.33) | TIPARP | |
| SCHEMBL22612334 | 0.76 | ATF4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237413-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022094244-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2022-05-05 | — | — | WO | disclosed |
| EP-3962906-A1 | SUBSTITUTED CYCLOALKYLS AS MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2022-03-09 | — | — | EP | disclosed |
| WO-2020223538-A1 | SUBSTITUTED CYCLOALKYLS AS MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2020-11-05 | — | — | WO | disclosed |