Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MGAM | O43451 | 4/20 | 0.47 |
| ▸ | SI | P14410 | 4/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813127 | 0.89 | LMNA (0.59) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL2715686 | 0.85 | LMNA (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| Oxyphenisatine SCHEMBL35387956 | 0.82 | CHRM2 (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| Oxyphenisatine SCHEMBL239513 | 0.82 | CHRM2 (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL25340217 | 0.80 | LMNA (0.76) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL17813124 | 0.79 | LMNA (0.69) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL22632192 | 0.79 | LMNA (0.80) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL2716060 | 0.79 | CHRM2 (0.93) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL11361033 | 0.78 | CHRM2 (0.69) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL17813120 | 0.78 | MAPT (0.69) | LMNACHRM2ADORA3KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336998-B1 | Highly soluble aromatic polyimides | DU PONT (US) | 1994-07-06 | — | — | EP | disclosed |
| US-4935490-A | Highly soluble aromatic polyimides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0336998-A1 | Highly soluble aromatic polyimides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-18 | — | — | EP | disclosed |